Backpressure Regulators

• Improve baseline stability by preventing bubble formation in the flow cell
• Adjustable backpressure between 0 - 105 bar (1500 psi) without disconnecting
• Biocompatible
• Low dead volume

Even properly degassed mobile phases may contain some dissolved gases that can release bubbles in the detector flow cell, resulting in baseline noise and drift. Our backpressure regulator provides a quick and convenient way to improve the stability of detector baseline by providing a constant backpressure on the flow cell, which stops the release of dissolved gases from the mobile phase. A spring-loaded FFKM (Perfluorinated rubber) diaphragm provides the force that generates the backpressure. Spring tension may be adjusted using the backpressure adjustment screw on the top of the regulator to vary the backpressure without disconnecting the regulator from the system.

Connections are made with fingertight fittings for 1/16" tubing. Because of the unique design, the backpressure regulator has only 0.6 µL internal volume. Installed between two detectors in a multidetector system, or between a detector and fraction collector system, or between a detector and fraction collector, it will not affect the peak shape. Typically, 90% or more of a given component's efficiency will be retained upon passing through the regulator. And the fluid path is completely biocompatible!

Backpressure Regulators